Publications

Publications 

Glioblastoma remodelling of human neural circuits decreases survival
Krishna S, Choudhury A, Keough MB, Seo K, Ni L, Kakaizada S, Lee A, Aabedi A, Popova G, Lipkin B, et al.
Nature

2023

Organic Matrix Derived from Host–Microbe Interplay Contributes to Pathological Renal Biomineralization
Bai Y, Wang Y, Kang M, Gabe CM, Srirangapatanam S, Edwards A, Stoller M, Green SJ, Aloni S, Tamura N, et al.
ACS Nanoscience Au

2023

Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity
Caruso JA, Wang X, Murrow LM, Rodriguez CI, Chen-Tanyolac C, Vu L, Chen YY, Gascard P, Gartner ZJ, Kerlikowske K, et al.
Proceedings of the National Academy of Sciences

2023

Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data
Patel RK, Jaszczak RG, Im K, Carey ND, Courau T, Bunis DG, Samad B, Avanesyan L, Chew NW, Stenske S, et al.
Frontiers in Immunology

2023

A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, et al.
Nature Communications

2023

The microenvironment dictates glycocalyx construction and immune surveillance
Tharp K, Park S, Timblin G, Richards A, Berg J, Twells N, Riley N, Peltan E, Shon D, Stevenson E, et al.
eLife

2023

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer
Zagorulya M, Yim L, Morgan D, Edwards A, Torres-Mejia E, Momin N, McCreery C, Zamora I, Horton B, Fox J, et al.
Immunity

2023

Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors
Beppler C, Eichorst J, Marchuk K, Cai E, Castellanos C, Sriram V, Roybal K, Krummel M
Journal of Cell Biology

2022

Discovering dominant tumor immune archetypes in a pan-cancer census
Combes A, Samad B, Tsui J, Chew N, Yan P, Reeder G, Kushnoor D, Shen A, Davidson B, Barczak A, et al.
Cell

2022

Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage
Rusu I, Mennillo E, Bain J, Li Z, Sun X, Ly K, Rosli Y, Naser M, Wang Z, Advincula R, et al.
The Journal of Clinical Investigation

2022

Visualizing Spatial and Stoichiometric Barriers to Bispecific T-Cell Engager Efficacy
You R, Artichoker J, Ray A, Gonzalez Velozo H, Rock D, Conner K, Krummel M
Cancer Immunology Research

2022

IL10 trains macrophage profibrotic function after lung injury
Bhattacharyya A, Boostanpour K, Bouzidi M, Magee L, Chen T, Wolters R, Torre P, Pillai S, Bhattacharya M
American Journal of Physiology-Lung Cellular and Molecular Physiology

2022

T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition
Cai E, Beppler C, Eichorst J, Marchuk K, Eastman S, Krummel M
Proceedings of the National Academy of Sciences

2022

Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation
Cautivo K, Matatia P, Lizama C, Mroz N, Dahlgren M, Yu X, Sbierski-Kind J, Taruselli M, Brooks J, Wade-Vallance A, et al.
Immunity

2022

ADAM8 signaling drives neutrophil migration and ARDS severity
Conrad C, Yildiz D, Cleary S, Margraf A, Cook L, Schlomann U, Panaretou B, Bowser J, Karmouty-Quintana H, Li J, et al.
JCI Insight

2022

Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain
Crouch E, Bhaduri A, Andrews M, Cebrian-Silla A, Diafos L, Birrueta J, Wedderburn-Pugh K, Valenzuela E, Bennett N, Eze U, et al.
Cell

2022

Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer
Kersten K, Hu K, Combes A, Samad B, Harwin T, Ray A, Rao A, Cai E, Marchuk K, Artichoker J, et al.
Cancer Cell

2022

IL-13–programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function
Kotas M, Moore C, Gurrola J, Pletcher S, Goldberg A, Alvarez R, Yamato S, Bratcher P, Shaughnessy C, Zeitlin P, et al.
JCI Insight

2022

Comparable Impairment of Vascular Endothelial Function by a Wide Range of Electronic Nicotine Delivery Devices
Rao P, Han D, Tan K, Mohammadi L, Derakhshandeh R, Navabzadeh M, Goyal N, Springer M
Nicotine & Tobacco Research

2022

Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung
Reyes N, Krasilnikov M, Allen N, Lee J, Hyams B, Zhou M, Ravishankar S, Cassandras M, Wang C, Khan I, et al.
Science

2022

A Superfolder Green Fluorescent Protein-Based Biosensor Allows Monitoring of Chloride in the Endoplasmic Reticulum
Shariati K, Zhang Y, Giubbolini S, Parra R, Liang S, Edwards A, Hejtmancik J, Ratto G, Arosio D, Ku G
ACS Sensors

2022

Species-specific sensitivity to TGFβ signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution
Smith S, Chu D, Qu T, Aggleton J, Schneider R
eLife

2022

Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
Valet C, Magnen M, Qiu L, Cleary S, Wang K, Ranucci S, Grockowiak E, Boudra R, Conrad C, Seo Y, et al.
The Journal of Clinical Investigation

2022

Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
Drain A, Zahir N, Northey J, Zhang H, Huang P, Maller O, Lakins J, Yu X, Leight J, Alston-Mills B, et al.
Journal of Experimental Medicine

2021

A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane
Frumm S, Yu S, Chang J, Artichoker J, Scaria S, Lee K, Byrnes L, Sneddon J, Tward A
Cell Stem Cell

2021